Balanced Bites Podcast #413: Supplements Liz Loves: Chatting with Primeadine creator Leslie Kenny about spermidine, anti-aging, and health

Leslie Kenny

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#413 Topics:

Purchase Primeadine (spermidine) signature and gluten-free at Oxford Healthspan:

Use code LIZ10 for 10% off your order!

Resistant starch & the gut biome

Spermidine, autophagy & inflammation

Spermidine from Primeadine vs. other sources

Leslie’s autoimmune journey of healing

Primeadine for hair, skin and nails

Primeadine for post-COVID hair shedding?
When to take Primeadine

Primeadine and leaky gut

Why to avoid synthetic or liposomal spermidine

Find Oxford Healthspan and the Oxford Longevity Project Online:



Balanced Bites Podcast #413 with Leslie Kenny

Welcome to the new Balanced Bites Podcast! I’m your host, Liz, a nutritional therapy practitioner and best selling author bringing you candid, up-front, myth-busting and thought-provoking conversations about food, fitness, and life. Remember:  The information in this podcast should not be considered personal, individual, or medical advice.

I have spent YEARS researching whether a good multivitamin is truly necessary for overall health. But the truth is, there are a LOT of opinions out there, including from people like me, who love to ask lots of obnoxious, overly detailed questions. But the truth is, if I’m paying attention to how I FEEL, my answer was clear: I will be taking my multivitamin. And it will be from the brand Needed. Needed third-party tests EVERY batch for performance and quality, which is incredibly rare in the supplement industry and also incredibly important to me! To get started with Needed, head to Use code balanced for 20% off your one-time order or your first three months’ subscription. While you’re at it, add Stress Support to your cart. I’m loving that one, too.

About Leslie Kenny

Today I’m talking to Leslie Kenny, who is the, Founder & CEO of Oxford Healthspan and the Co-Founder of the Oxford Longevity Project

Oxford Healthspan produces one of the few supplements I actually make sure to take every day. And I’ll talk about that in a moment. But first, more on Leslie.

Leslie is a Southern Californian entrepreneur and graduate of both Berkeley and Harvard, whose life was turned upside down when she was diagnosed with lupus and rheumatoid arthritis in her 30s. And we talk more about that in the course of this podcast. When her doctors told her lupus had a life expectancy of five years and that RA could only be managed, not cured, she set out to optimize her health as best she could with safe, natural solutions.

She went back to school at the Institute for Integrative Nutrition in NYC, became a Bulletproof coach under health pioneer Dave Asprey, and took on health coaching clients worldwide.

At the same time, she began helping life science academics at European universities, including Oxford (where she lives), to raise money for their discoveries. At a meeting with one such scientist, she also learned about a natural compound called spermidine, which is abundant in nattō, a traditional Japanese dish that she had grown up with.

Spermidine was showing great promise supporting health as we age.

The science was compelling – one scientist even called it “an anti-aging vitamin” in a published scientific journal – and it was safe. Still, because it was natural, food-derived, and not a drug that would bring in more money, no one was interested in promoting it.

Leslie immediately wanted her octogenarian mother back home in California to take it – especially since nattō is very hard to come by (and it’s pretty smelly!) Unfortunately, spermidine wasn’t available in the US (or really even known there). Spotting this unmet need, she decided to bring it to the US herself.

Today, at age 57, Leslie is living proof that we can get better with age, so long as we take responsibility for our health and meet our doctors halfway.

Spermidine is part of her anti-aging arsenal, and she hopes it will become part of yours too.

So again. The supplement is called Primeadine.

And I have it by my sink and I take it before bed every night. I began to take it for post covid hair loss, but it has a lot of other benefits as well in anti aging, hair skin and nails, autophagy (cellular cleanup), sleep enhancement, and according to Leslie, it inhibits 9 of the 12 signs of aging, and you know I’m all about that.

What I like about it, and what we talk about in this interview, is that it contains the poly amines spermidine, spermine, AND putrescene. And can fairly I think be called a spermidine complex because we have not just isolated one nutrient in this supplement, we actually have those auxiliary nutrients as well. I recognize side note that those are terrible names. And the origin of the name spermidine is pretty close to what you might think it is. But it’s not AS bad as it might sound, so get your mind out of the gutter a little bit.

And here’s something I want to disclaim quickly.

It is a BIG priority of mine to have people on who are the driving forces behind companies and products I love. Selfishly, because I want to ask all my own questions of them. But also because one of the things that has been consistent in my entire career doing this is: people want to know what *I* am using and why. That’s why I am bringing on folks who are behind the products I love. It’s not because they ask to come on and advertise themselves. In fact, I decline quite a few of those types of interviews because it’s just not authentic to what I’m actually doing or taking or researching.

There are times, here and there, that I will get a free bottle of something, or a discount as an affiliate, but another benefit of me being an affiliate is that I can usually offer you all a discount as well; but most often, I’m buying these products for myself because I believe in them so much.

So with that, Go to the link in this podcast description and Use code LIZ10 for 10% off your order from Oxford Healthspan. Let’s start our chat with Leslie!

Thanks for listening to the new Balanced Bites Podcast! Before you shut down your podcast app, PLEASE take a moment to subscribe and leave a review! It’s a small thing you can do that I appreciate more than you can imagine! And speaking of what we can do for each other, if YOU have a question you’d like to have tackled on this podcast or an interview you’d like to hear, submit the details at Let’s keep unpacking, unraveling, contextualizing and nuance-ing the important questions together so we can be empowered, informed, active participants in our own health and happiness.

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